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Design of a standardized system for transfer of patients with ST-elevation myocardial infarction for percutaneous coronary intervention

Study of:

Background:
Direct percutaneous coronary intervention (PCI) is the preferred method of reperfusion for ST-elevation myocardial infarction (STEMI). Transfer from community hospitals to PCI centers increases availability for direct PCI, which improves outcomes compared to fibrinolysis in Europe. It has been difficult to achieve similar door-to-balloon times for transfer patients in the United States.

Methods:
We designed a standardized protocol and integrated system of transfer for patients with STEMI. We report the door-to-balloon times for the pre- and postpilot patients in the index hospital and describe the details of the current Level 1 MI Program.

Results:
In the 15 months before the pilot project, the door-to-balloon time for patients receiving ad hoc transfer for direct PCI was 192 minutes, similar to the national average. The door-to-balloon time for the patients receiving rescue PCI after failed thrombolysis was 221 minutes. The standardized protocol decreased door-to-balloon time to 98 minutes in the pilot trial ( P b .01) and has now been applied successfully in 29 community hospitals.

Conclusion:
Rapid transfer of patients with STEMI is feasible in the United States using a standardized protocol and integrated transfer system. This requires a team approach with cooperation between cardiologists, emergency physicians, nurses, and the emergency medical system as well as various health care organizations. (Am Heart J 2005;150:373-84.)

For more information on this study, choose the following link to download .pdf of this trial design.
(Adobe Reader is required; click on the "Get Acrobat Reader" button below to open a new window to the Adobe Web site, and to download free software.)

Investigator(s)

Bjorn P. Flygenring, MD, FACC 

Timothy D. Henry, MD, FACC 

Daniel Lips, MD, FACC 

James D. Madison, MD, FACC 

Michael R. Mooney, MD, FACC 

Wesley R. Pedersen, MD, FACC 

Scott W. Sharkey, MD, FACC 

Barbara Unger, RN, BS, FAACVPR

For more information about this study or other research studies at the Minneapolis Heart Institute and Minneapolis Heart Institute Foundation, please contact Katie Menssen at 612-775-3052.

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